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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 74601Generated: October 26, 2026

(4-Chloro-5-iodo-pyridin-2-yl)-(5-fluoro-2,3-dihydro-indol-1-yl)-methanone → HCID 58386674, compound

https://huagongshe.com/reaction/74601

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chloro-5-iodo-pyridin-2-yl)-(5-fluoro-2,3-dihydro-indol-1-yl)-methanoneHCID 58386447—
ReactantHCID 178418260HCID 178418260—
SolventDimethylformamideHCID 6228—
ProductHCID 58386674HCID 58386674—

Reaction Steps

Under a nitrogen atmosphere 45 mg (0.50 mmol) copper cyanide were added to 0.10 g (0.25 mmol) (4-chloro-5-iodo-pyridin-2-yl)-(5-fluoro-2,3-dihydro-indol-1-yl)-methanone in 1.5 mL DMF and the mixture was stirred for 2 h at RT. The reaction mixture was stirred overnight at 100° C. and then mixed with d-water. The precipitate formed was suction filtered and dried.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829006B2
Source datasetuspto-grants-2014_09
ORD IDord-d110e930734343f8b6d81af4e3a6f28a
Source noteuspto-grants-2014_09