Thionyl Chloride → HCID 178455739, compound

HRID 746114Notes

Reaction equation

HRID 746114 reaction equation
[CH2:1]([C@H:3]1[CH2:8][CH2:7][C@H:6]([CH2:9][CH2:10][C:11]2[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=2)[CH2:5][CH2:4]1)[CH3:2].S(Cl)([Cl:22])=O>>[CH2:1]([C@H:3]1[CH2:8][CH2:7][C@H:6]([CH2:9][CH2:10][C:11]2[CH:19]=[CH:18][C:14]([C:15]([Cl:22])=[O:16])=[CH:13][CH:12]=2)[CH2:5][CH2:4]1)[CH3:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 178455740HCID 178455740, compound

Product 1

HCID 178455739HCID 178455739, compoundYield 100%

Procedure

4-[2-(trans-4-Ethylcyclohexyl)ethyl]-benzoic acid (10.5 gram, 40.38 m moles) prepared as in Example 2 was refluxed with thionyl chloride (60 ml) for 1 hour. The excess thionyl chloride was then distilled off to give 4-[2-(trans-4-ethylcyclohexyl)ethyl]benzoyl chloride (11.2 gram 100% of theory).

Workup

  1. distillationThe excess thionyl chloride was then distilled off

Sources & evidence

ORD record
ord-adb4285a4d8d4bc7bc26a95fea4f7a70
Source dataset
uspto-grants-1986_07
Patent number
US04602851

Reaction notes

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