Benzoyl chloride → HCID 23512730, compound

Participants

Reaction Steps

Using the general method of Example 186 1-(8-aminooctyl)-1H-imidazo[4,5-c]quinolin-4-amine (3.85 mmol) was reacted with benzoyl choride (450 μL, 3.85 mmol) to provide 0.45 g of N-[8-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)octyl]benzamide as an off white powder, m.p. 133.1-136.7° C. Analysis: Calculated for C25H29N5O.0.25H2O: % C, 71.49; % H, 7.08; % N, 16.67; Found: % C, 71.37; % H, 7.05; % N, 16.62.

Provenance & Evidence