Butyryl chloride → HCID 23512718, compound

Participants

Reaction Steps

Using the general method of Example 197, 1-(4-aminobutyl)-2-methyl-1H-imidazo[4,5-c]quinolin-4-amine (1.00 g, 3.7 mmol) was reacted with butyryl chloride (0.43 mL, 4.1 mmol) to provide 0.65 g of N-[4-(4-amino-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]butanamide as an off white solid, m.p. 169.4-170.5° C.

Provenance & Evidence