Butyryl chloride → HCID 23512673, compound

Participants

Reaction Steps

Using the general method of Example 205, 1-(3-aminopropyl)-2-methyl-1H-imidazo[4,5-c]quinolin4-amine (2.00 g, 7.83 mmol) was reacted with butyryl chloride (835 mg, 7.83 mmol). The product was recrystallized from methanol to provide 1.07 g of N-[3-(4-amino-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]butanamide as a white powder, m.p. 221.8-223.3° C. Analysis: Calculated for C18H23N5O.0.25 CH4O: % C, 65.74; % H, 7.26; % N, 21.00; Found: % C, 65.79; % H, 7.14; % N, 21.25.

Provenance & Evidence