HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bms-973013 → HCID 58386605, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bms-973013 | HCID 22293182 | — |
| Reactant | (2-Chloro-pyridin-4-yl)-(5,6-difluoro-2,3-dihydro-indol-1-yl)-methanone | HCID 58386704 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 58386605 | HCID 58386605 | — |
Reaction Steps
1.0 g (4.6 mmol) 1-piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one, 0.45 g (1.5 mmol) (2-chloro-pyridin-4-yl)-(5,6-difluoro-2,3-dihydro-indol-1-yl)-methanone were stirred in 4 mL of NMP for 4 h at 130° C. The reaction mixture was purified by HPLC. The product-containing fractions were combined and freeze-dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829006B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-032d9bc1f83c41c89fa34d6aa31f8612 |
| Source note | uspto-grants-2014_09 |