HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dihydroxybutanedioic Acid → (R)-2-(3-(Diisopropylamino)-1-phenylpropyl)-4-methylphenol 2,3-dihydroxysuccinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| Reactant | Tolterodine | HCID 443879 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (R)-2-(3-(Diisopropylamino)-1-phenylpropyl)-4-methylphenol 2,3-dihydroxysuccinate | HCID 9847786 | 68.4% |
Reaction Steps
Tolterodine free base (5.0 gm) is dissolved in ethanol (75 ml) and tartaric acid (3.0 gm) is added to the solution. Then the contents are stirred for 2 hours at 25° C. to 30° C. and filtered to give 5.0 gm of tolterodine tartrate form I.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07393874B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-a6760cbb426c4e7ea503d0f6ac02f7ed |
| Source note | uspto-grants-2008_07 |