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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 746685Generated: October 30, 2026

Methyl 4-(3-amino-1H-pyrazol-5-yl)benzoate → HCID 178497538, compound

https://huagongshe.com/reaction/746685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(3-amino-1H-pyrazol-5-yl)benzoateHCID 57342040—
ReactantHCID 178418806HCID 178418806—
ReactantHCID 178517101HCID 178517101—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178497538HCID 178497538—

Reaction Steps

The named compound is prepared by substituting 4-(5-amino-2H-pyrazol-3-yl)-benzoic acid methyl ester for 3-aminopyrazole in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one (0.100 gms.) is reacted with 0.2847 gms. of 4-(5-amino-2H-pyrazol-3-yl)-benzoic acid methyl ester by refluxing in tetrahydrofuran (2.5 mL).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07393870B2
Source datasetuspto-grants-2008_07
ORD IDord-1420861993bc447c9363500f4c742d81
Source noteuspto-grants-2008_07