Water → HCID 69328936, compound

Participants

Reaction Steps

Add SnCl2.2 H2O (8.5 mmol) to a solution of propane-2-sulfonic acid [2-(3′-fluoro-5′-nitro-biphenyl-4-yl)-thiophen-3-yl]-amide (1.2 mmol) in EtOH (40 mL). Heat the reaction at 70° C. for 30 min and then at room temperature overnight. Add a saturated solution of NaHCO3 (pH=11-12) and extract with EtOAc (2×50 mL). Dry over NaSO4, filter and evaporate to dryness to provide the title compound. MS (ES−): 389 (M−1).

Provenance & Evidence