Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Cinacalcet Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Cinacalcet | HCID 156419 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Cinacalcet Hydrochloride | HCID 156418 | — |
반응 단계
Cinacalcet base is dissolved in absolute ethanol (4 volumes per gram of cinacalcet base). Then 1N HCl (1.5 eq.) is added drop-wise. The obtained mixture is stirred at room temperature for 20 hours to obtain a precipitate. The product is isolated by filtration, washed with water, and dried in a vacuum oven at 50° C. for 24 hours to obtain Cinacalcet hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07393967B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-c46f9d004a72491fb1bf102a4660f79b |
| 출처 메모 | uspto-grants-2008_07 |