HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 746912Generated: October 31, 2026
HCID 69018910, compound → HCID 69017599, compound
https://huagongshe.com/reaction/746912
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 69018910 | HCID 69018910 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 69017599 | HCID 69017599 | 96.7% |
Reaction Steps
cis-4-t-Butyloxycarbonylamino-1-benzyl-3-methylpiperidine (13 g, 0.042 mol) was dissolved in 170 ml methanol and transferred to the Parr pressure reactor after addition of 1.3 g of Pd(OH)2 on carbon. The rqcytoion mixture stirred for 6 hrs at 400 psi pressure at 50° C. Catalyst was removed by filtration and eavaporation of the solvent afforded 8.7 g (95%) of titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07393957B2 |
|---|
| Source dataset | uspto-grants-2008_07 |
|---|
| ORD ID | ord-c48ce15a73be4c0da230f154354cfea9 |
|---|
| Source note | uspto-grants-2008_07 |
|---|