反应详情

温度

70 °C

20.1 g of acrylonitrile was added dropwise to an aqueous solution (150 ml) of 15.5 g of hexylamine at room temperature over 0.5 hours, and then the mixed solution was stirred at 70° C. for 3 hours. After standing to cool to room temperature, the mixed solution was extracted with 150 ml of ethyl acetate. The organic layer was separated from the solution, dried over anhydrous magnesium sulfate, and distilled off the solvent to obtain 31.4 g of a target compound as a colorless oily product.

1. temperatureto cool to room temperature
2. extractionthe mixed solution was extracted with 150 ml of ethyl acetate
3. customThe organic layer was separated from the solution
4. dry with materialdried over anhydrous magnesium sulfate
5. distillationdistilled off the solvent