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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747136Generated: October 26, 2026

7-Aminoquinoline → N-(6-chloro-4-pyrimidinyl)-7-Quinolinamine

https://huagongshe.com/reaction/747136

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-AminoquinolineHCID 11377—
ReactantPotassium CarbonateHCID 11430—
Reactant4,6-DichloropyrimidineHCID 70943—
SolventDimethylformamideHCID 6228—
ProductN-(6-chloro-4-pyrimidinyl)-7-QuinolinamineHCID 22135502—

Reaction Steps

This compound could be prepared from 4,6-dichloro-pyrimidine and 7-aminoquinoline in the presence of K2CO3 and DMF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07396831B2
Source datasetuspto-grants-2008_07
ORD IDord-6f1ed880d5314f49af2e614b8111c039
Source noteuspto-grants-2008_07