Ethane, 1-fluoro-2-iodo- → 5-[2-Amino-4,6-di(2-furyl)-5-pyrimidinyl]-1-(2-fluoroethyl)-1,2-dihydro-2-pyridinone

HRID 747174Notes

Reaction equation

HRID 747174 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]2[CH:14]=[CH:15][C:16](=[O:19])[NH:17][CH:18]=2)=[C:4]([C:20]2[O:21][CH:22]=[CH:23][CH:24]=2)[N:3]=1.I[CH2:26][CH2:27][F:28]>>[NH2:1][C:2]1[N:3]=[C:4]([C:20]2[O:21][CH:22]=[CH:23][CH:24]=2)[C:5]([C:13]2[CH:14]=[CH:15][C:16](=[O:19])[N:17]([CH2:26][CH2:27][F:28])[CH:18]=2)=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

3

Reactant 2

HCID 69804Ethane, 1-fluoro-2-iodo-HCID 597491455-[2-Amino-4,6-di(2-furyl)-5-pyrimidinyl]-1,2-dihydro-2-pyridinone

Product 1

HCID 597491435-[2-Amino-4,6-di(2-furyl)-5-pyrimidinyl]-1-(2-fluoroethyl)-1,2-dihydro-2-pyridinone

Procedure

The title compound was synthesized in a similar manner to Example 66 using 5-[2-amino-4,6-di(2-furyl)-5-pyrimidinyl]-1,2-dihydro-2-pyridinone and 1-iodo-2-fluoroethane.

Sources & evidence

ORD record
ord-e8b200b624dd46db9ae565bdd865b9c3
Source dataset
uspto-grants-2008_07
Patent number
US07396836B2

Reaction notes

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