反应详情

(5R)-5-(Azidomethyl)-3-(5-bromopyrid-2-yl)-1,3-oxazolidin-2-one (5.60 g, 18.7 mM) was dissolved in thioacetic acid (10 ml) to give a yellow solution. The solution was degassed and stirred at room temperature for 20 hours. The thick slurry was concentrated and the desired product was crystallized from acetone (100 ml) to give the product as a light yellow solid (3.25 g).

1. customto give a yellow solution
2. customThe solution was degassed
3. concentrationThe thick slurry was concentrated
4. customthe desired product was crystallized from acetone (100 ml)