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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747231Generated: October 29, 2026

(S)-N-[3-(3-Fluoro-4-iodo-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide → HCID 59749512, compound

https://huagongshe.com/reaction/747231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-N-[3-(3-Fluoro-4-iodo-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamideHCID 11222662—
ReactantHCID 59749469HCID 59749469—
ProductHCID 59749512HCID 5974951257.7%

Reaction Steps

Using essentially the same procedure as Example 28, but starting from N-{[(5S)-3-(3-fluoro-4-iodophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide (0.38 g, 1.00 mM) and adding (5R)-5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3-[3-fluoro-4-(trimethylstannyl)phenyl]-1,3-oxazolidin-2-one (0.73 g, 1.50 mM) gave the title compound as a light yellow solid (0.334 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07396847B2
Source datasetuspto-grants-2008_07
ORD IDord-813fa6faeba145d4ada2d2d24f142285
Source noteuspto-grants-2008_07