HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-(Dimethylamino)propyl)-N'-phenylthiourea → N-{3-[3-(Dimethylamino)propyl]-5-phenylthiazol-2(3H)-ylidene}aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-(Dimethylamino)propyl)-N'-phenylthiourea | HCID 1982459 | — |
| Reactant | 2-Bromo-2-phenylacetaldehyde | HCID 10888901 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-{3-[3-(Dimethylamino)propyl]-5-phenylthiazol-2(3H)-ylidene}aniline | HCID 22350922 | 53.8% |
Reaction Steps
Using N-[3-(dimethylamino)propyl]-N′-phenylthiourea (650 mg) obtained in Reference Example 3 as described below, 2-bromo-2-phenylacetoaldehyde (600 mg) and N,N-dimethylformamide (11 ml), the title compound (497 mg) was obtained in a similar manner to in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07396842B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-79b44d3f87cd41f99901e4df207669d3 |
| Source note | uspto-grants-2008_07 |