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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747503Generated: October 29, 2026

Hydrochloric Acid → HCID 22351003, compound

https://huagongshe.com/reaction/747503

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactantt-butyl 3-[4-(4-methoxyphenyl)-2-(phenylimino)thiazol-3(2H)-yl]propylcarbamateHCID 22351001—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 22351003HCID 22351003122.7%

Reaction Steps

A mixture of t-butyl 3-[4-(4-methoxyphenyl)-2-(phenylimino)-thiazol-3(2H)-yl]propylcarbamate (400 mg) and a 4N solution of hydrogen chloride in dioxane (8 ml) was stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure, and to the residue was added diethyl ether. The insoluble salt was collected by filtration to give the title compound (379 mg) as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07396842B2
Source datasetuspto-grants-2008_07
ORD IDord-692a4af97287428bb06cfaada5974a65
Source noteuspto-grants-2008_07