tert-butyl N-(4-aminobutyl)carbamate → HCID 22351020, compound

HRID 747536Notes

Reaction equation

HRID 747536 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][C:8](=[S:12])SCC.[NH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:24])([CH3:23])[CH3:22]>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][C:8]([NH:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:23])([CH3:22])[CH3:24])=[S:12]

Participants

3

Reactant 2

HCID 4351tert-butyl N-(4-aminobutyl)carbamateHCID 12214896Ethyl 2-Pyridyldithiocarbamate

Product 1

HCID 22351020HCID 22351020, compoundYield 340.3%

Procedure

Ethyl 2-pyridyldithiocarbamate (500 mg) and t-butyl 4-amino-butylcarbamate (474 mg) were reacted in a similar manner to in Reference Example 58, and crystallized from n-hexane-diethyl ether to give the title compound (2.78 g).

Workup

  1. customcrystallized from n-hexane-diethyl ether

Sources & evidence

ORD record
ord-8d18219bb23f4383b50601f5fc9fd694
Source dataset
uspto-grants-2008_07
Patent number
US07396842B2

Reaction notes

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