tert-Butyl (3-aminopropyl)carbamate → HCID 22350956, compound

HRID 747537Notes

Reaction equation

HRID 747537 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([NH:9][C:10](=[S:13])SC)=[N:7][CH:8]=1.[NH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:24])([CH3:23])[CH3:22]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([NH:9][C:10]([NH:14][CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:23])([CH3:22])[CH3:24])=[S:13])=[N:7][CH:8]=1

Participants

3

Reactant 2

HCID 2735700tert-Butyl (3-aminopropyl)carbamateHCID 22351016HCID 22351016, compound

Product 1

HCID 22350956HCID 22350956, compoundYield 100.1%

Procedure

Methyl 5-methoxy-2-pyridyldithiocarbamate (950 mg) and t-butyl 3-aminopropylcarbamate (772 mg) were treated in a similar manner to in Reference Example 58, and crystallized from n-hexane-ethanol to give the title compound (1.51 g).

Workup

  1. customcrystallized from n-hexane-ethanol

Sources & evidence

ORD record
ord-e5afc94b78e448d6b1bf475767e4b75d
Source dataset
uspto-grants-2008_07
Patent number
US07396842B2

Reaction notes

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