5-(Methoxycarbonyl)thiophene-2-carboxylic acid → HCID 48664408, compound

HRID 747580Notes

Reaction equation

HRID 747580 reaction equation
[N:1]1([C:7]2[CH:12]=[CH:11][C:10]([CH:13]([NH2:15])[CH3:14])=[CH:9][CH:8]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:16][O:17][C:18]([C:20]1[S:21][C:22]([C:25](O)=[O:26])=[CH:23][CH:24]=1)=[O:19]>>[CH3:16][O:17][C:18]([C:20]1[S:21][C:22]([C:25](=[O:26])[NH:15][CH:13]([C:10]2[CH:9]=[CH:8][C:7]([N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)=[CH:12][CH:11]=2)[CH3:14])=[CH:23][CH:24]=1)=[O:19]

Participants

3

Reactant 2

HCID 8183525-(Methoxycarbonyl)thiophene-2-carboxylic acidHCID 49128101-(4-Morpholin-4-yl-phenyl)-ethylamine

Product 1

HCID 48664408HCID 48664408, compound

Procedure

The title compound was prepared in an analogous manner to that described in example 1, step 1 from 1-(4-Morpholin-4-yl-phenyl)-ethylamine and thiophene-2,5-dicarboxylic acid monomethyl ester.

Sources & evidence

ORD record
ord-65114214930f4393af0e7aab8fed1dde
Source dataset
uspto-grants-2008_07
Patent number
US07396944B2

Reaction notes

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