HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 6-Chloro-2-methyl-4H-3,1-benzoxazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Amino-5-chlorobenzoic acid | HCID 12476 | — |
| Product | 6-Chloro-2-methyl-4H-3,1-benzoxazin-4-one | HCID 291134 | — |
Reaction Steps
To 15 g of 2-amino-5-chlorobenzoic acid are added 80 ml of acetic anhydride, and the mixture is refluxed for 2 hours. The reaction medium is concentrated and the residue is recrystallized from ethanol. After filtering off and rinsing the precipitate, 10.25 g of the expected product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07396958B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-749d375a8fed4fc7a00a82d46da9bf2c |
| Source note | uspto-grants-2008_07 |