Dimethylformamide → 4-Formylbenzoyl chloride

Participants

Reaction Conditions

Reaction Steps

To a solution of 4-carboxybenzaldehyde (4.50 g, 30 mmol) in CHCl3 (6 mL) and DCM (5 mL), containing a catalytic amount of DMF, was added oxalyl chloride (7.7 mL, 90 mmol). The mixture was stirred at 50° C. for 3 hours. The reaction was concentrated in vacuo and the residue was dried.

Provenance & Evidence