2,2-Dimethyl-5-(3-methylbutanoyl)-1,3-dioxane-4,6-dione → Ethyl 5-methyl-3-oxohexanoate

Participants

Reaction Steps

Compound 9 was dissolved in EtOH (150 mL) and refluxed overnight. The reaction mixture was evaporated to yield product (10.315 g), which was shown by NMR to be pure. 1H NMR (500 MHz, CDCl3): δ 0.93 (d, 6H), 1.28 (t, 3H), 2.16 (m, 1H), 2.42 (d, 2H), 3.41 (2, 2H), 4.20 (q, 2H).

Provenance & Evidence