反应详情

2.96 g (11.5 mmol) of ethyl 4-ethoxycarbonimidoylbenzoate hydrochloride and 690 mg (11.5 mmol) of ethylenediamine were stirred in 100 ml of ethanol at 60° C. for 4 hours. The solvent was evaporated. 1 N aqueous sodium hydroxide solution was added to the residue. After the extraction with dichloromethane followed by the washing with saturated Aqueous NaCl solution and drying over anhydrous magnesium sulfate, the solvent was evaporated to obtain the title compound.

1. customThe solvent was evaporated
2. addition1 N aqueous sodium hydroxide solution was added to the residue
3. extractionAfter the extraction with dichloromethane
4. dry with materialdrying over anhydrous magnesium sulfate
5. customthe solvent was evaporated