Triethyl phosphite → Methyl 4-(diethoxyphosphorylmethyl)benzoate

Participants

Reaction Steps

6.64 g (40 mmol) of triethyl phosphite was added to 2.29 g (10 mmol) of methyl 4-(bromomethyl)benzoate, and the resultant mixture was stirred at 150° C. for 19 hours. The mixture was purified by the silica gel column chromatography to obtain the title compound.

Provenance & Evidence