HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 4-(4,5-dihydro-1H-imidazol-2-yl)benzoate → ethyl 4-(1H-imidazol-2-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 4-(4,5-dihydro-1H-imidazol-2-yl)benzoate | HCID 22709787 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | ethyl 4-(1H-imidazol-2-yl)benzoate | HCID 17788902 | — |
Reaction Steps
500 mg (2.3 mmol) of ethyl 4-(2-imidazoline-2-yl)benzoate and 500 mg of 10% palladium/carbon were heated in 20 ml of toluene under reflux in argon atmosphere for 9 hours. The reaction liquid was diluted with ethyl acetate and filtered through Celite. The filtrate was concentrated to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07396844B1 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-3aae55ec152741afa79a5cde7036aec0 |
| Source note | uspto-grants-2008_07 |