HCID 57045305, compound → 4-(Dimethylcarbamoyl)benzoic acid

HRID 747781Notes

Reaction equation

HRID 747781 reaction equation
C([O:5]C(N[C@@H](CCOC1C=CC=C(C#N)C=1)C(OCC1C=CC=CC=1)=O)=O)(C)(C)C.[CH3:31][N:32]([CH3:66])[C:33]([C:35]1[CH:65]=[CH:64][C:38]([C:39](N[C@@H](CCOC2C=CC=C(C#N)C=2)C(OCC2C=CC=CC=2)=O)=[O:40])=[CH:37][CH:36]=1)=[O:34]>>[CH3:66][N:32]([CH3:31])[C:33]([C:35]1[CH:36]=[CH:37][C:38]([C:39]([OH:40])=[O:5])=[CH:64][CH:65]=1)=[O:34]

Participants

3

Reactant 2

HCID 57045305HCID 57045305, compoundHCID 57262441HCID 57262441, compound

Product 1

HCID 110954804-(Dimethylcarbamoyl)benzoic acid

Procedure

The title compound was obtained in the same manner as in step 6 in Example 1 by treating benzyl (2S)-2-t-butoxycarbonylamino-4-(3-cyanophenoxy)butyrate (the compound in step 1 in Example 91) and benzyl (2S)-2-(4-dimethylcarbamoylbenzoylamino)-4-(3-cyanophenoxy)butyrate obtained in the same manner as in step 2 in Example 91 from 4-dimethylcarbamoylbenzoic acid as the starting material.

Sources & evidence

ORD record
ord-745f71b330b144fc872cd5fdccf6a4db
Source dataset
uspto-grants-2008_07
Patent number
US07396844B1

Reaction notes

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