5-Methyl-3-phenylisoxazole-4-carbonyl chloride → HCID 58946090, compound

Participants

Reaction Steps

As described for example 1a, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid chloride (0.266 g, 1.2 mmol) was converted, by using 6-aminomethyl-nicotinonitrile hydrochloride salt (0.17 g, 1 mmol) instead of 2-picolylamine, to the title compound (296 mg, 93%) which was obtained as a white solid. MS: m/e: 319.0 [M+H]+.

Provenance & Evidence