Paeonol → 3-(2,4-Dimethoxy-pyrimidin-5-yl)-7-methoxy-4-methyl-chromen-2-one

HRID 747870Notes

Reaction equation

HRID 747870 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[C:10](=O)[CH3:11].[CH3:13][O:14][C:15]1[N:20]=[C:19]([O:21][CH3:22])[C:18]([CH2:23][C:24](O)=[O:25])=[CH:17][N:16]=1>>[CH3:13][O:14][C:15]1[N:20]=[C:19]([O:21][CH3:22])[C:18]([C:23]2[C:24](=[O:25])[O:1][C:2]3[C:3]([C:10]=2[CH3:11])=[CH:4][CH:5]=[C:6]([O:8][CH3:9])[CH:7]=3)=[CH:17][N:16]=1

Participants

3

Reactant 2

HCID 11092PaeonolHCID 552675012,4-Dimethoxy-5-pyrimidineacetic acid

Product 1

HCID 116742933-(2,4-Dimethoxy-pyrimidin-5-yl)-7-methoxy-4-methyl-chromen-2-one

Procedure

The title product was prepared as a white solid according to the procedure described in Example 9 using 1-(2-hydroxy-4-methoxy-phenyl)-ethanone and (2,4-dimethoxy-pyrimidin-5-yl)-acetic acid as the starting material.

Sources & evidence

ORD record
ord-ca0ca91d2f8b41f6a153a357670f8176
Source dataset
uspto-grants-2008_07
Patent number
US07399767B2

Reaction notes

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