HCID 11737629, compound → 3-(2,4-Dimethoxy-pyrimidin-5-yl)-4-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-chromen-2-one

HRID 747871Notes

Reaction equation

HRID 747871 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][O:10][CH2:11][CH2:12][Si:13]([CH3:16])([CH3:15])[CH3:14])[CH:5]=[CH:4][C:3]=1[C:17](=O)[CH3:18].[CH3:20][O:21][C:22]1[N:27]=[C:26]([O:28][CH3:29])[C:25]([CH2:30][C:31](O)=[O:32])=[CH:24][N:23]=1>>[CH3:20][O:21][C:22]1[N:27]=[C:26]([O:28][CH3:29])[C:25]([C:30]2[C:31](=[O:32])[O:1][C:2]3[C:3]([C:17]=2[CH3:18])=[CH:4][CH:5]=[C:6]([O:8][CH2:9][O:10][CH2:11][CH2:12][Si:13]([CH3:16])([CH3:15])[CH3:14])[CH:7]=3)=[CH:24][N:23]=1

Participants

3

Reactant 2

HCID 11737629HCID 11737629, compoundHCID 552675012,4-Dimethoxy-5-pyrimidineacetic acid

Product 1

HCID 116479593-(2,4-Dimethoxy-pyrimidin-5-yl)-4-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-chromen-2-one

Procedure

The title product was prepared as a white solid according to the procedure described in Example 9 using 1-[2-hydroxy-4-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-ethanone and (2,4-dimethoxy-pyrimidin-5-yl)-acetic acid as the starting material.

Sources & evidence

ORD record
ord-bb64561930334b37b47e8746dcaa494e
Source dataset
uspto-grants-2008_07
Patent number
US07399767B2

Reaction notes

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