HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 59750664, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-Chloronicotinamide | HCID 80456 | — |
| Reactant | 6-HYDROXY-2-TETRALONE | HCID 4575996 | — |
| Product | HCID 59750664 | HCID 59750664 | 49% |
Reaction Steps
Using a method similar to Intermediate 1, using 6-hydroxy-2-tetralone (Journal of Organic Chemistry (1999), 64(26), 9719-9721.) (1.55 g, 9.55 mmol), 6-chloronicotinamide (1.49 g, 9.55 mmol) and K2CO3 (1.98 g, 14.3 mmol) gives the title compound (1.32 g), after purification on silica gel (50% THF/DCM), as an amber foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07399774B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-72a85fd498f6480f909a777ad54beabf |
| Source note | uspto-grants-2008_07 |