Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747950Generated: October 28, 2026

Potassium Carbonate → HCID 59750664, compound

https://huagongshe.com/reaction/747950

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant6-ChloronicotinamideHCID 80456—
Reactant6-HYDROXY-2-TETRALONEHCID 4575996—
ProductHCID 59750664HCID 5975066449%

Reaction Steps

Using a method similar to Intermediate 1, using 6-hydroxy-2-tetralone (Journal of Organic Chemistry (1999), 64(26), 9719-9721.) (1.55 g, 9.55 mmol), 6-chloronicotinamide (1.49 g, 9.55 mmol) and K2CO3 (1.98 g, 14.3 mmol) gives the title compound (1.32 g), after purification on silica gel (50% THF/DCM), as an amber foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07399774B2
Source datasetuspto-grants-2008_07
ORD IDord-72a85fd498f6480f909a777ad54beabf
Source noteuspto-grants-2008_07