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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 748034Generated: October 29, 2026

Acetate → methyl 2-((1R,3S)-3-hydroxycyclohexyloxymethyl)-6-methylbenzoate

https://huagongshe.com/reaction/748034

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantHCID 86601919HCID 86601919—
Productmethyl 2-((1R,3S)-3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 11492838—

Reaction Steps

The enantiomer 2-((1S,3R)-3-hydroxycyclohexyloxymethyl)-6-methylbenzoate is generated from the acetate obtained in the chromatography forerun after saponification and re-methylation, and is used to prepare the corresponding enantiomeric example structures.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07399777B2
Source datasetuspto-grants-2008_07
ORD IDord-6d61f7618dff450daa9a45993890e51d
Source noteuspto-grants-2008_07