5-(1-azido-2-ethylbutyl)-1-(4-methoxybenzyl)-1H-pyrazole → {2-ethyl-1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butyl}amine

Participants

Reaction Steps

5-(1-Azido-2-ethylbutyl)-1-(4-methoxybenzyl)-1H-pyrazole (0.750 g, 2.39 mmol) in MeOH (24 mL) with 5% Pd/C (75 mg) was hydrogenated under atm pressure for 24 h. The reaction mixture was filtered through a plug of Celite and the filtrate was concentrated to give 0.637 g (93%) of {2-ethyl-1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butyl}amine as an oil.

Provenance & Evidence