Isobutyraldehyde → 2-Methyl-1-(1-phenyl-1H-pyrazol-5-yl)propan-1-ol

HRID 748051Notes

Reaction equation

[C:1]1([N:7]2[CH:11]=[CH:10][CH:9]=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:12](=[O:16])[CH:13]([CH3:15])[CH3:14]>>[CH3:14][CH:13]([CH3:15])[CH:12]([C:11]1[N:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[N:8]=[CH:9][CH:10]=1)[OH:16]

Participants

Reactant 2

HCID 6561Isobutyraldehyde

HCID 707691-Phenylpyrazole

Product 1

HCID 685933562-Methyl-1-(1-phenyl-1H-pyrazol-5-yl)propan-1-olYield 57%

Procedure

This compound was prepared from 1-phenyl-1H-pyrazole and isobutyraldehyde using the method described in example 10B and isolated as a clear oil in 57% yield.

Workup

customisolated as a clear oil in 57% yield

Sources & evidence

ORD record: ord-a480b8738e5b4d1399de58db51136bfd
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07399778B2

Reaction notes

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