HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine-2-carbonitrile → HCID 59750420, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine-2-carbonitrile | HCID 7522 | — |
| Reactant | 4-Chloro-2-sulfanylbenzoic acid | HCID 20456974 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 59750420 | HCID 59750420 | 48% |
Reaction Steps
A mixture of 4-chloro-2-mercaptobenzoic acid (6.00 g, 31.8 mmol), 2-cyanopyridine (1.90 g, 17.7 mmol) and pyridine (50.0 ml) was refluxed for 9 hrs as described in Example 9. After cooling, the precipitated crystals were collected by filtration and recrystallized from hexane-chlorobenzene to give the titled compound (2.30 g, 48%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07399759B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-57a60b0532724cf9b01d722bbcadb12e |
| Source note | uspto-grants-2008_07 |