HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 59750455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | Ethyl 6-cyanopyridine-2-carboxylate | HCID 13415158 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 59750455 | HCID 59750455 | 80.7% |
Reaction Steps
A mixture of methyl thiosalicylate (2.0 g, 11.9 mmol), ethyl 6-cyano-2-pyridinecarboxylate (2.1 g, 11.9 mmol), triethylamine (3.0 ml, 21.5 mmol) and toluene (6 ml) was refluxed for 12 hrs as described in Example 1. The precipitated crystals were collected by filtration and recrystallized from diisopropylether-tetrahydrofuran to give the titled compound (3.0 g, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07399759B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-09e3977e93a84453a2128a31eb78934a |
| Source note | uspto-grants-2008_07 |