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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 748249Generated: October 30, 2026

HCID 22939293, compound → 3-[6-(7-Fluoro-4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propionic acid

https://huagongshe.com/reaction/748249

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22939293HCID 22939293—
SolventTrifluoroacetic acidHCID 6422—
Product3-[6-(7-Fluoro-4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propionic acidHCID 59750458100.1%

Reaction Conditions

Temperature0 °C

Reaction Steps

tert-Butyl 3-[6-(7-fluoro-4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propanoate (0.50 g, 1.3 mmol) was dissolved in trifluoroacetic acid (5 ml), and the mixture was stirred at 0° C. for 2 hrs. The solvent was evaporated, and the residue was crystallized from diethyl ether to give the titled compound (0.43 g, 99%) as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07399759B2
Source datasetuspto-grants-2008_07
ORD IDord-f8f192c3f34447ceaced0d487c045372
Source noteuspto-grants-2008_07