HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 748249Generated: October 30, 2026
HCID 22939293, compound → 3-[6-(7-Fluoro-4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propionic acid
https://huagongshe.com/reaction/748249
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 22939293 | HCID 22939293 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 3-[6-(7-Fluoro-4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propionic acid | HCID 59750458 | 100.1% |
Reaction Steps
tert-Butyl 3-[6-(7-fluoro-4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propanoate (0.50 g, 1.3 mmol) was dissolved in trifluoroacetic acid (5 ml), and the mixture was stirred at 0° C. for 2 hrs. The solvent was evaporated, and the residue was crystallized from diethyl ether to give the titled compound (0.43 g, 99%) as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07399759B2 |
|---|
| Source dataset | uspto-grants-2008_07 |
|---|
| ORD ID | ord-f8f192c3f34447ceaced0d487c045372 |
|---|
| Source note | uspto-grants-2008_07 |
|---|