5-Bromo-2-oxindole → 5-(2-Furyl)-1,3-dihydro-2H-indol-2-one

HRID 748525Notes

Reaction equation

HRID 748525 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2.C([Sn](CCCC)(CCCC)[C:17]1[O:18][CH:19]=[CH:20][CH:21]=1)CCC>>[O:18]1[CH:19]=[CH:20][CH:21]=[C:17]1[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2

Participants

3

Reactant 2

HCID 6111935-Bromo-2-oxindoleHCID 43936882-(Tributylstannyl)furan

Product 1

HCID 166375135-(2-Furyl)-1,3-dihydro-2H-indol-2-one

Procedure

The title compound was prepared as described for Example 37 using 5-bromooxindole and tri-n-butyl(2-furyl)tin: MS (ES) m/z 200 (M++1).

Sources & evidence

ORD record
ord-7810aa182a8a41d4b1d5fda2842fc7ec
Source dataset
uspto-grants-2008_07
Patent number
US07399780B2

Reaction notes

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