huagongshe.com
HRID74883

反应详情

EQUATION

反应方程式

HRID 74883 反应方程式

REACTANTS

反应物

3
Trimethylsilyl isocyanate 分子结构式
HCID70696

Trimethylsilyl isocyanate

C4H9NOSi

HCID 67284924 分子结构式
HCID67284924

未命名化合物

2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-(1-(cyclopentyl-methylsulfonyl)azetidin-3-yl)-5-fluoropyrimidin-4-amine 分子结构式
HCID68007937

2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-(1-(cyclopentyl-methylsulfonyl)azetidin-3-yl)-5-fluoropyrimidin-4-amine

C20H22ClFN6O2S

PRODUCTS

产物

1
HCID 86762724 分子结构式
HCID86762724

未命名化合物

收率 79%

PROCEDURE

实验过程

According to the procedure for compound 469 using 61 mg (0.11 mmol) of 6c and isocyanatotrimethylsilane (15.14 μL, 0.11 mmol) afforded 87 mg (79% yield) of 512, as a white solid: