Hydrochloric Acid → HCID 68519458, compound

Participants

Reaction Steps

Dissolve the compound of Example 38 (30 mg, 0.051 mmol) in dry dichloromethane (1 mL) and add 2M HCl in diethyl ether (0.10 mL, 0.20 mmol). Stir at room temperature for 1 minute. Remove the solvent by blowing nitrogen over the liquid. Place the residue on a high vacuum pump for 1 hour. Dry the product in a vacuum oven at 45° C. overnight to yield 30 mg of the title compound (97%): mass spectrum (ion spray) m/z=586.3 (M+H—HCl).

Provenance & Evidence