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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 749064Generated: October 26, 2026

p-Fluoronitrobenzene → 4-(2-Carboxymethoxyphenoxy)nitrobenzene

https://huagongshe.com/reaction/749064

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-FluoronitrobenzeneHCID 9590—
Reactant(o-Hydroxyphenoxy)acetic acidHCID 22783—
ReactantPotassium butoxideHCID 23699084—
SolventDimethylacetamideHCID 31374—
Product4-(2-Carboxymethoxyphenoxy)nitrobenzeneHCID 22048504—

Reaction Steps

4-nitro-fluorobenzene and 2-(carboxymethoxy)phenol were reacted together in DMA in the presence of potassium butoxide for 2 hours at 150° C. to yield 4-(2-carboxymethoxyphenoxy)nitrobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07402583B2
Source datasetuspto-grants-2008_07
ORD IDord-d2405a0feb124c4698ac834bcf8a55e8
Source noteuspto-grants-2008_07