Ethanol → HCID 69318858, compound

Participants

Reaction Steps

A solution of 3-(4-{[6-(Benzyl{(2R)-2-[8-(benzyloxy)-2-oxo-1,2-dihydroquinolin-5-yl]-2-hydroxyethyl}amino)hexyl]oxy}butyl)benzenesulfonamide (10 mg) in ethanol (10 ml) and acetic acid (0.1 ml) was stirrer under hydrogen in the presence of palladium on charcoal (5 mg) for 2 h. The reaction mixture was filtered and concentrated in vacuo. The residue was purified by chromatography (SPE, gradient from DCM to DCM-MeOH—NH3(aq) 100:10:1) and freeze-dried from water-acetic acid to give the title compound (5.8 mg).

Provenance & Evidence