4-Chloroaniline → HCID 9796374, compound

HRID 749312Notes

Reaction equation

HRID 749312 reaction equation
C([O:8][C:9]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:10]=1[CH:11]=[C:12]([C:19]([OH:21])=O)[N:13]2[CH3:18])C1C=CC=CC=1.[Cl:22][C:23]1[CH:29]=[CH:28][C:26]([NH2:27])=[CH:25][CH:24]=1>>[Cl:22][C:23]1[CH:29]=[CH:28][C:26]([NH:27][C:19]([C:12]2[N:13]([CH3:18])[C:14]3[C:10]([CH:11]=2)=[C:9]([OH:8])[CH:17]=[CH:16][CH:15]=3)=[O:21])=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 78124-ChloroanilineHCID 47776784-Benzyloxy-1-methyl-1H-indole-2-carboxylic acid

Product 1

HCID 9796374HCID 9796374, compound

Procedure

From 4-benzyloxy-1-methyl-1H-indole-2-carboxylic acid and 4-chloroaniline the title compound was prepared by a method analogous to that described in Example 11. MS ES (M++H)=301 and 303.

Sources & evidence

ORD record
ord-1b1c71e3c04840d990f757a0919f1850
Source dataset
uspto-grants-2008_07
Patent number
US07402604B2

Reaction notes

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