HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → (R)-N-(2-Azido-1-benzylethyl)-4-hydroxy-1-methyl-1H-indole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | (R)-2-azido-1-benzylethylamine | HCID 14802497 | — |
| Reactant | 3-Hydroxy-1-methyl-1H-indole-2-carboxylic acid | HCID 54711425 | — |
| Product | (R)-N-(2-Azido-1-benzylethyl)-4-hydroxy-1-methyl-1H-indole-2-carboxamide | HCID 86601455 | — |
Reaction Steps
From (R)-2-azido-1-benzylethylamine (prepared as described by Horwell, et al., J. Med. Chem., 1991, 404-414) and 4 hydroxy-1-methyl-1H-indole-2-carboxylic acid the title compound was prepared by a method analogous to that described in Example 13. MS ES (M++H)=350; [α]D=+94.8° (MeOH, C=1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402604B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-81e0566dba6b411db778eb9a23341747 |
| Source note | uspto-grants-2008_07 |