HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → 2-Benzyl-2-(2,2,2-trifluoroethyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-(Phenylmethyl)propanedinitrile | HCID 15846 | — |
| Reactant | 2,2,2-Trifluoroethyl trifluoromethanesulfonate | HCID 80366 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Benzyl-2-(2,2,2-trifluoroethyl)malononitrile | HCID 22235011 | 55.5% |
Reaction Steps
Using 0.1 g of benzylmalononitrile, 5 ml of N,N-dimethylformamide, 0.073 g of cesium carbonate, and 0.1 g of 2,2,2-trifluoroethyl trifluoromethanesulfonate, and according to the process described in the Production Example 1, there was obtained 0.057 g of 2-benzyl-2-(2,2,2-trifluoroethyl)malononitrile (the present compound (3)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-6c709c2162a5461d965f19b5ab0a6509 |
| Source note | uspto-grants-2008_07 |