HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → 2-(2,2,3,3,3-Pentafluoropropyl)-2-(4-(trifluoromethoxy)benzyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate | HCID 2776019 | — |
| Reactant | (4-(Trifluoromethoxy)benzyl)malononitrile | HCID 22235052 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(2,2,3,3,3-Pentafluoropropyl)-2-(4-(trifluoromethoxy)benzyl)malononitrile | HCID 22235048 | 29% |
Reaction Steps
Using 0.3 g of (4-(trifluoromethoxy)benzyl)malononitrile, 5 ml of N,N-dimethylformamide, 0.073 g of cesium carbonate, and 0.35 g of 2,2,3,3,3-pentafluoropropyl trifluoromethanesulfonate, and according to the process described in the Production Example 1, there was obtained 0.12 g of 2-(2,2,3,3,3-pentafluoropropyl)-2-(4-(trifluoromethoxy)benzyl)malononitrile (the present compound (5)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-062feb08cf88480ab7deb784467f5087 |
| Source note | uspto-grants-2008_07 |