HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22235017, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Reactant | 2-(4-nitrobenzyl)malononitrile | HCID 2764146 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235017 | HCID 22235017 | 11% |
Reaction Steps
Using 5.00 g of (4-nitrobenzyl)malononitrile, 60 ml of N,N-dimethylformamide, 1.10 g of sodium hydride (60% in oil), and 4.85 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.80 g of 2-(4-nitrobenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (18)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-0d334d7b662c48b78916b3abca46564d |
| Source note | uspto-grants-2008_07 |