HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22235006, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Reactant | HCID 11286827 | HCID 11286827 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235006 | HCID 22235006 | 27.4% |
Reaction Steps
Using 1.00 g of (4-cyanobenzyl)malononitrile, 10 ml of N,N-dimethylformamide, 0.36 g of sodium hydride (60% in oil), and 2.37 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.42 g of 2-(4-cyanobenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (22)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-80a1975923b34dd2a375be6bf1bc6f60 |
| Source note | uspto-grants-2008_07 |