HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 2-(3,4,4-Trifluoro-3-butenyl)-2-(4-(trifluoromethylthio)benzyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Bromo-1,1,2-trifluorobut-1-ene | HCID 66333 | — |
| Reactant | (4-(Trifluoromethylthio)benzyl)malononitrile | HCID 22234991 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(3,4,4-Trifluoro-3-butenyl)-2-(4-(trifluoromethylthio)benzyl)malononitrile | HCID 22235024 | 17% |
Reaction Steps
Using 0.50 g of (4-(trifluoromethylthio)benzyl)malononitrile, 10 ml of N,N-dimethylformamide, 86 mg of sodium hydride (60% in oil), and 0.74 g of 4-bromo-1,1,2-trifluoro-1-butene, and according to the process described in the Production Example 1, there was obtained 0.12 g of 2-(3,4,4-trifluoro-3-butenyl)-2-(4-(trifluoromethylthio)benzyl)malononitrile (the present compound (54)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-4ab554aaac3348fbbbf0ce06d460477f |
| Source note | uspto-grants-2008_07 |